Natural History of Knee Cartilage Defects and Factors Affecting Change
نویسندگان
چکیده
منابع مشابه
Natural history of knee cartilage defects and factors affecting change.
BACKGROUND Knee cartilage defects may play an important role in early osteoarthritis, but little is known about their natural history. METHODS Knee cartilage defect score (range, 0-4), cartilage volume, and bone surface area were determined using T1-weighted fat-saturated magnetic resonance imaging in 325 subjects (mean age, 45 years) at baseline and 2 years later. RESULTS Thirty-three perc...
متن کاملFactors affecting progression of knee cartilage defects in normal subjects over 2 years.
OBJECTIVES Cartilage defects are present in subjects with knee osteoarthritis (OA). Although they are often present in healthy subjects, there is little data on the natural history of cartilage defects. The aim of this study was to examine the change in cartilage defects over 2 yr and to identify factors associated with this change. METHODS One hundred and twenty-four healthy subjects underwe...
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OBJECTIVES To understand the factors that influence joint cartilage in health and disease as they are important for the prevention and management of osteoarthritis. METHODS We conducted a cross-sectional study to determine factors influencing knee cartilage volume in 45 males aged (mean+/-S.D.) 52.5+/-13.2 yr. RESULTS Total and medial tibial volumes were inversely associated with age, body ...
متن کاملTreatment options for articular cartilage defects of the knee.
The treatment of symptomatic articular cartilage defects of the knee has evolved tremendously in the past decade. Previously, there were limited treatment options available to patients who suffered from either partial-thickness or full-thickness cartilage lesions. Because articular cartilage has a limited capacity for healing, patients were often treated symptomatically until they became candid...
متن کاملParticulated articular cartilage for symptomatic chondral defects of the knee.
The treatment of focal cartilage defects in the knee remains a challenging clinical problem. One relatively new unique treatment option is particulated articular cartilage, which includes autograft and off-the-shelf allogeneic juvenile grafts. The use of particulated cartilage has the advantage of being a single-stage procedure. In the case of autograft, it is cost efficient, while in the juven...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 2006
ISSN: 0003-9926
DOI: 10.1001/archinte.166.6.651